Alterations in Serum Myostatin Levels via Swimming Exercise in High Fructose Mediated Metabolic Syndrome Model

Aims: Metabolic syndrome is a table of abdominal diseases characterized by insulin resistance, obesity, dyslipidemia, and hypertension, it serious risk factor for the development cardiovascular diseases. The purpose this study was to understand how metabolic causes change in myostatin levels, if swimming exercise have protective therapeutic effects fructose mediated model regulating serum level.
 Methodology: A total 21 Sprague Dawley male rats were used study. induced adding 30% into drinking water 5 weeks (6-8 old, weighing 200-250 g) randomly divided 3 groups as 7 each cage. Swimming exercises applied three days week six weeks. On days, exercised 20 minutes day. Blood collected from all animals aprotinin tubes be necessary analysis with decapitation. Serum samples obtained after centrifugation kept at -80 ℃ until assay performed. In samples, measured ELISA method.
 Results: There statistically significant difference resulting G2, which had highest value glucose triglyceride levels between groups. G2 lowest HDL levels. Myostatin significantly higher compared other groups.
 Conclusion: Moderate are preventing chronic such diabetes, obesity syndrome. line these results, can said that practice regulates impaired fasting glucose, increased TG decreased downregulates